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Dependence of Internal Friction on Folding Mechanism

[Image: see text] An outstanding challenge in protein folding is understanding the origin of “internal friction” in folding dynamics, experimentally identified from the dependence of folding rates on solvent viscosity. A possible origin suggested by simulation is the crossing of local torsion barrie...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Zheng, Wenwei, De Sancho, David, Hoppe, Travis, Best, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379956/
https://ncbi.nlm.nih.gov/pubmed/25721133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja511609u
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