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A re-formulation of generalized linear mixed models to fit family data in genetic association studies
The generalized linear mixed model (GLMM) is a useful tool for modeling genetic correlation among family data in genetic association studies. However, when dealing with families of varied sizes and diverse genetic relatedness, the GLMM has a special correlation structure which often makes it difficu...
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Publicado no: | Front Genet |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379931/ https://ncbi.nlm.nih.gov/pubmed/25873936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00120 |
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