Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway hyperresponsiveness

Mechanisms underlying airway hyperresponsiveness are not yet fully elucidated. One of the manifestations of airway inflammation is leakage of diverse plasma proteins into the airway lumen. They include fibrinogen and thrombin. Thrombin cleaves fibrinogen to form fibrin, a major component of thrombi....

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Pubblicato in:J Clin Invest
Autori principali: Wagers, Scott S., Norton, Ryan J., Rinaldi, Lisa M., Bates, Jason H.T., Sobel, Burton E., Irvin, Charles G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC437962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15232617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19569
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