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Both ERK1 and ERK2 Are Required for Enterovirus 71 (EV71) Efficient Replication

It has been demonstrated that MEK1, one of the two MEK isoforms in Raf-MEK-ERK1/2 pathway, is essential for successful EV71 propagation. However, the distinct function of ERK1 and ERK2 isoforms, the downstream kinases of MEKs, remains unclear in EV71 replication. In this study, specific ERK siRNAs a...

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Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Zhu, Meng, Duan, Hao, Gao, Meng, Zhang, Hao, Peng, Yihong
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379574/
https://ncbi.nlm.nih.gov/pubmed/25803100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7031344
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