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Both ERK1 and ERK2 Are Required for Enterovirus 71 (EV71) Efficient Replication

It has been demonstrated that MEK1, one of the two MEK isoforms in Raf-MEK-ERK1/2 pathway, is essential for successful EV71 propagation. However, the distinct function of ERK1 and ERK2 isoforms, the downstream kinases of MEKs, remains unclear in EV71 replication. In this study, specific ERK siRNAs a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Viruses
Prif Awduron: Zhu, Meng, Duan, Hao, Gao, Meng, Zhang, Hao, Peng, Yihong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379574/
https://ncbi.nlm.nih.gov/pubmed/25803100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7031344
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