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The Dynamic Conformational Cycle of the Group I Chaperonin C-Termini Revealed via Molecular Dynamics Simulation

Chaperonins are large ring shaped oligomers that facilitate protein folding by encapsulation within a central cavity. All chaperonins possess flexible C-termini which protrude from the equatorial domain of each subunit into the central cavity. Biochemical evidence suggests that the termini play an i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dalton, Kevin M., Frydman, Judith, Pande, Vijay S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379175/
https://ncbi.nlm.nih.gov/pubmed/25822285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117724
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