Safety of Voriconazole and Sirolimus Coadministration after Allogeneic Hematopoietic Stem Cell Transplantation

Antifungal prophylaxis with azoles is considered standard in allogeneic hematopoietic stem-cell transplant (allo-HCT). Although sirolimus is being used increasingly for prevention of graft-versus-host disease (GVHD), it is a substrate of CYP3A4, which is inhibited by voriconazole, and concurrent adm...

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Detalhes bibliográficos
Publicado no:Bone Marrow Transplant
Main Authors: Ceberio, Izaskun, Dai, Kefei, Devlin, Sean M., Barke, Juliet N., Castro-Malaspina, Hugo, Goldberg, Jenna D., Giralt, Sergio, Adel, Nelly G., Perales, Miguel-Angel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379043/
https://ncbi.nlm.nih.gov/pubmed/25599164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2014.286
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