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Deficiency of Angulin-2/ILDR1, a Tricellular Tight Junction-Associated Membrane Protein, Causes Deafness with Cochlear Hair Cell Degeneration in Mice

Tricellular tight junctions seal the extracellular spaces of tricellular contacts, where the vertices of three epithelial cells meet, and are required for the establishment of a strong barrier function of the epithelial cellular sheet. Angulins and tricellulin are known as specific protein component...

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Publicat a:PLoS One
Autors principals: Higashi, Tomohito, Katsuno, Tatsuya, Kitajiri, Shin-ichiro, Furuse, Mikio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378975/
https://ncbi.nlm.nih.gov/pubmed/25822906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120674
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