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Scoring Large Scale Affinity Purification Mass Spectrometry Datasets with MIST

High-throughput Affinity Purification Mass Spectrometry (AP-MS) experiments can identify a large number of protein interactions but only a fraction of these interactions are biologically relevant. Here, we describe a comprehensive computational strategy to process raw AP-MS data, perform quality con...

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Bibliografische gegevens
Gepubliceerd in:Curr Protoc Bioinformatics
Hoofdauteurs: Verschueren, Erik, Von Dollen, John, Cimermancic, Peter, Gulbahce, Natali, Sali, Andrej, Krogan, Nevan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378866/
https://ncbi.nlm.nih.gov/pubmed/25754993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471250953.bi0819s49
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