The roles of stress-activated Sty1 and Gcn2 kinases and proto-oncoprotein homologue Int6/eIF3e in responses to endogenous oxidative stress during histidine starvation

In fission yeast, Sty1 and Gcn2 are important protein kinases regulating gene expression in response to amino acid starvation. The translation factor subunit eIF3e/Int6 promotes the Sty1-dependent response by increasing the abundance of Atf1, a transcription factor targeted by Sty1. While Gcn2 promo...

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Vydáno v:J Mol Biol
Hlavní autoři: Nemoto, Naoki, Udagawa, Tsuyoshi, Ohira, Takahiro, Jiang, Li, Hirota, Kouji, Wilkinson, Caroline R. M., Bähler, Jürg, Jones, Nic, Ohta, Kunihiro, Wek, Ronald C., Asano, Katsura
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378542/
https://ncbi.nlm.nih.gov/pubmed/20875427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.09.016
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