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Silencing of UCHL1 by CpG Promoter Hyper-Methylation is Associated With Metastatic Gastroenteropancreatic Well-Differentiated Neuroendocrine (Carcinoid) Tumors

BACKGROUND: Well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare tumors with varying metastatic potential. The underlying molecular basis for metastasis by GEP-NETs remains undefined. METHODS: Quantitative PCR and immunohistochemistry (IHC) staining for ubiquitin carb...

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Detalhes bibliográficos
Publicado no:Ann Surg Oncol
Main Authors: Kleiman, David A., Beninato, Toni, Sultan, Samuel, Crowley, Michael J.P., Finnerty, Brendan, Kumar, Ritu, Panarelli, Nicole C., Liu, Yi-Fang, Lieberman, Michael D., Seandel, Marco, Evans, Todd, Elemento, Olivier, Zarnegar, Rasa, Fahey, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378537/
https://ncbi.nlm.nih.gov/pubmed/24854489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3787-2
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