Pleiotropic effects of extended blockade of CSF1R signaling in adult mice

We investigated the role of CSF1R signaling in adult mice using prolonged treatment with anti-CSF1R antibody. Mutation of the CSF1 gene in the op/op mouse produces numerous developmental abnormalities. Mutation of the CSF1R has an even more penetrant phenotype, including perinatal lethality, because...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Leukoc Biol
Hlavní autoři: Sauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Tsai, Yi Ting, Bradford, Barry M., Raza, Sobia, Moffat, Lindsey, Gow, Deborah J., Beard, Philippa M., Mabbott, Neil A., Smith, Lee B., Hume, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2014
Témata:
Receptors, Signal Transduction, & Genes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378363/
https://ncbi.nlm.nih.gov/pubmed/24652541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0114-006R
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky