Pleiotropic effects of extended blockade of CSF1R signaling in adult mice

We investigated the role of CSF1R signaling in adult mice using prolonged treatment with anti-CSF1R antibody. Mutation of the CSF1 gene in the op/op mouse produces numerous developmental abnormalities. Mutation of the CSF1R has an even more penetrant phenotype, including perinatal lethality, because...

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Bibliografiset tiedot
Julkaisussa:J Leukoc Biol
Päätekijät: Sauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Tsai, Yi Ting, Bradford, Barry M., Raza, Sobia, Moffat, Lindsey, Gow, Deborah J., Beard, Philippa M., Mabbott, Neil A., Smith, Lee B., Hume, David A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Leukocyte Biology 2014
Aiheet:
Receptors, Signal Transduction, & Genes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378363/
https://ncbi.nlm.nih.gov/pubmed/24652541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0114-006R
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