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Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology

BACKGROUND: The peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor that regulates lipid catabolism and inflammation and is hepatocarcinogenic in rodents. It is presumed that the functions of PPARα in liver depend on cross-talk between parenchymal (hep...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Szalowska, Ewa, Tesfay, Haftu A, van Hijum, Sacha A F T, Kersten, Sander
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378209/
https://ncbi.nlm.nih.gov/pubmed/25511156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1106
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