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Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors.

Using the 9L experimental brain tumor model, we studied long-term tumor regression and immunologic consequences of tumor killing in a model of in vivo gene transfer of the herpes simplex virus 1 thymidine kinase (HSV-TK) gene and ganciclovir (GCV) treatments. Fibroblasts modified to produce retrovir...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Barba, D, Hardin, J, Sadelain, M, Gage, F H
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1994
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4348
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