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An evolutionarily conserved DNA architecture determines target specificity of the TWIST family bHLH transcription factors
Basic helix–loop–helix (bHLH) transcription factors recognize the canonical E-box (CANNTG) to regulate gene transcription; however, given the prevalence of E-boxes in a genome, it has been puzzling how individual bHLH proteins selectively recognize E-box sequences on their targets. TWIST is a bHLH t...
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Izdano u: | Genes Dev |
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Glavni autori: | , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Cold Spring Harbor Laboratory Press
2015
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4378193/ https://ncbi.nlm.nih.gov/pubmed/25762439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.242842.114 |
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