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Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis

BACKGROUND: Marine sponges are important sources of bioactive compounds. OBJECTIVE: This study investigated the anticancer properties of Hyattella cribriformis ethyl acetate (EA) fraction in various cancer and normal cell lines. MATERIALS AND METHODS: anticancer assay was carried out in 15 cell line...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacogn Mag
Hauptverfasser: Annamalai, Pazhanimuthu, Thayman, Malini, Rajan, Sowmiya, Raman, Lakshmi Sundaram, Ramasubbu, Sankar, Perumal, Pachiappan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378133/
https://ncbi.nlm.nih.gov/pubmed/25829774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.153088
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