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Curtailing Endothelial TGF-β Signaling Is Sufficient to Reduce Endothelial-Mesenchymal Transition and Fibrosis in CKD

Excessive TGF-β signaling in epithelial cells, pericytes, or fibroblasts has been implicated in CKD. This list has recently been joined by endothelial cells (ECs) undergoing mesenchymal transition. Although several studies focused on the effects of ablating epithelial or fibroblast TGF-β signaling o...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Xavier, Sandhya, Vasko, Radovan, Matsumoto, Kei, Zullo, Joseph A., Chen, Robert, Maizel, Julien, Chander, Praveen N., Goligorsky, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378095/
https://ncbi.nlm.nih.gov/pubmed/25535303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013101137
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