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Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells.

Experimental approaches which exploit the targeted cytolytic activity of lymphocytes are being developed for cancer therapy. We generated cytotoxic T lymphocytes (CTLs) with specificity for ERBB2 receptor-expressing tumor cells. A binding function was conferred directly on the zeta chain of the T-ce...

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Detalhes bibliográficos
Main Authors: Moritz, D, Wels, W, Mattern, J, Groner, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43776/
https://ncbi.nlm.nih.gov/pubmed/7910405
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