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Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells.

Experimental approaches which exploit the targeted cytolytic activity of lymphocytes are being developed for cancer therapy. We generated cytotoxic T lymphocytes (CTLs) with specificity for ERBB2 receptor-expressing tumor cells. A binding function was conferred directly on the zeta chain of the T-ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moritz, D, Wels, W, Mattern, J, Groner, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43776/
https://ncbi.nlm.nih.gov/pubmed/7910405
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