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Uncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation

Wu-tou decoction (WTD) has been extensively used for the treatment of rheumatoid arthritis (RA). Due to lack of appropriate methods, pharmacological mechanisms of WTD acting on RA have not been fully elucidated. In this study, a list of putative targets for compositive compounds containing in WTD we...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Zhang, Yanqiong, Bai, Ming, Zhang, Bo, Liu, Chunfang, Guo, Qiuyan, Sun, Yanqun, Wang, Danhua, Wang, Chao, Jiang, Yini, Lin, Na, Li, Shao
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377576/
https://ncbi.nlm.nih.gov/pubmed/25820382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09463
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