Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis

Background. Previous studies, including ours, have examined the regulation of microRNAs (miRNAs) by DNA methylation, but whether this regulation occurs at a genome-wide level in hepatocellular carcinoma (HCC) is unclear. Subjects/Methods. Using a two-phase study design, we conducted genome-wide scre...

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Detalhes bibliográficos
Publicado no:Gastroenterol Res Pract
Main Authors: Shen, Jing, Wang, Shuang, Siegel, Abby B., Remotti, Helen, Wang, Qiao, Sirosh, Iryna, Santella, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377534/
https://ncbi.nlm.nih.gov/pubmed/25861255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/230642
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