Genome-Wide Expression of MicroRNAs Is Regulated by DNA Methylation in Hepatocarcinogenesis

Background. Previous studies, including ours, have examined the regulation of microRNAs (miRNAs) by DNA methylation, but whether this regulation occurs at a genome-wide level in hepatocellular carcinoma (HCC) is unclear. Subjects/Methods. Using a two-phase study design, we conducted genome-wide scre...

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Dettagli Bibliografici
Pubblicato in:Gastroenterol Res Pract
Autori principali: Shen, Jing, Wang, Shuang, Siegel, Abby B., Remotti, Helen, Wang, Qiao, Sirosh, Iryna, Santella, Regina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377534/
https://ncbi.nlm.nih.gov/pubmed/25861255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/230642
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