Splenic architecture disruption and parasite-induced splenocyte activation and anergy in Plasmodium falciparum-infected Saimiri sciureus monkeys

BACKGROUND: The understanding of the mechanisms of immunity in malaria is crucial for the rational development of interventions such as vaccines. During blood stage infection, the spleen is considered to play critical roles in both immunity and immunopathology of Plasmodium falciparum infections. ME...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Alves, Francisco A, Pelajo-Machado, Marcelo, Totino, Paulo RR, Souza, Mariana T, Gonçalves, Evonnildo C, Schneider, Maria Paula C, Muniz, José APC, Krieger, Marco A, Andrade, Marcia CR, Daniel-Ribeiro, Cláudio Tadeu, Carvalho, Leonardo JM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377215/
https://ncbi.nlm.nih.gov/pubmed/25890318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0641-3
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