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Dissecting metal ion-dependent folding and catalysis of a single DNAzyme

Protein metalloenzymes use various modes for functions where metal–dependent global conformational change is required in some cases, but not in others. In contrast, most ribozymes appear to require a global folding that almost always precedes enzyme reactions. Herein we studied metal–dependent foldi...

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Bibliographic Details
Published in:Nat Chem Biol
Main Authors: Kim, Hee-Kyung, Rasnik, Ivan, Liu, Juewen, Ha, Taekjip, Lu, Yi
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376948/
https://ncbi.nlm.nih.gov/pubmed/17965708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.45
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