Gut Microbiota and Tacrolimus Dosing in Kidney Transplantation

Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition. In view of the reported impact of gut microbial species on drug metabolism, we investi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, John R., Muthukumar, Thangamani, Dadhania, Darshana, Taur, Ying, Jenq, Robert R., Toussaint, Nora C., Ling, Lilan, Pamer, Eric, Suthanthiran, Manikkam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376942/
https://ncbi.nlm.nih.gov/pubmed/25815766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122399
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