Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease

BACKGROUND/AIMS: In the present study, we examined whether DNA methylation of the brain-derived neurotrophic factor (BDNF) promoter is associated with the manifestation and clinical presentation of Alzheimer's disease (AD). METHODS: Of 20 patients with AD and 20 age-matched normal controls (NCs...

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Veröffentlicht in:Dement Geriatr Cogn Dis Extra
Hauptverfasser: Nagata, Tomoyuki, Kobayashi, Nobuyuki, Ishii, Jumpei, Shinagawa, Shunichiro, Nakayama, Ritsuko, Shibata, Nobuto, Kuerban, Bolati, Ohnuma, Tohru, Kondo, Kazuhiro, Arai, Heii, Yamada, Hisashi, Nakayama, Kazuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2015
Schlagworte:
Original Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376924/
https://ncbi.nlm.nih.gov/pubmed/25873928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000375367
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