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The Ubiquitin Ligase UBE3A Dampens ERK Pathway Signalling in HPV E6 Transformed HeLa Cells

Signalling through the ERK MAP kinase pathway plays an important role in many biological processes and it is often deregulated in disease states such as cancer. One major effect of MAP kinase signalling is to promote gene expression through the phosphorylation and activation of transcription factors...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Aguilar-Martinez, Elisa, Morrisroe, Claire, Sharrocks, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376912/
https://ncbi.nlm.nih.gov/pubmed/25815718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119366
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