Lipopolysaccharide-Induced Middle Ear Inflammation Disrupts the cochlear Intra-Strial Fluid–Blood Barrier through Down-Regulation of Tight Junction Proteins

Middle ear infection (or inflammation) is the most common pathological condition that causes fluid to accumulate in the middle ear, disrupting cochlear homeostasis. Lipopolysaccharide, a product of bacteriolysis, activates macrophages and causes release of inflammatory cytokines. Many studies have s...

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Pubblicato in:PLoS One
Autori principali: Zhang, Jinhui, Chen, Songlin, Hou, Zhiqiang, Cai, Jing, Dong, Mingmin, Shi, Xiaorui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376743/
https://ncbi.nlm.nih.gov/pubmed/25815897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122572
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