Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation

Infection with Japanese encephalitis virus (JEV) can induce the expression of pro-inflammatory cytokines and cause acute encephalitis in humans. β-oxidation breaks down fatty acids for ATP production in mitochondria, and impaired β-oxidation can induce pro-inflammatory cytokine expression. To addres...

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Vydáno v:PLoS Pathog
Hlavní autoři: Kao, Yu-Ting, Chang, Bi-Lan, Liang, Jian-Jong, Tsai, Hang-Jen, Lee, Yi-Ling, Lin, Ren-Jye, Lin, Yi-Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376648/
https://ncbi.nlm.nih.gov/pubmed/25816318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004750
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