Inhibition of type I NKT cells by retinoids or following sulfatide-mediated activation of type II NKT cells attenuates alcoholic liver disease

Innate immune mechanisms leading to liver injury following chronic alcohol ingestion are poorly understood. Natural killer T (NKT) cells, enriched in the liver and comprised of at least two distinct subsets, type I and type II, recognize different lipid antigens presented by CD1d molecules. We have...

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Publicat a:Hepatology
Autors principals: Maricic, Igor, Sheng, Huiming, Marrero, Idania, Seki, Ehikiro, Kisseleva, Tatiana, Chaturvedi, Som, Molle, Natasha, Mathews, K. Stephanie, Gao, Bin, Kumar, Vipin
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376634/
https://ncbi.nlm.nih.gov/pubmed/25477000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27632
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