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Prolonged hypoxia induces MCT4 expression in MSCs resulting in a secretome that is deleterious to cardiovascular repair
MSCs encounter extended hypoxia in the wound microenvironment yet little is known about their adaptability to this prolonged hypoxic milieu. In this study, we evaluated the cellular and molecular response of MSCs in extended hypoxia (1% O(2)) vs. normoxia (20% O(2)) culture. Prolonged hypoxia induce...
में बचाया:
| में प्रकाशित: | Stem Cells |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376598/ https://ncbi.nlm.nih.gov/pubmed/25537659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1935 |
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