Tumoral TP53 and/or CDKN2A Alterations are Not Reliable Prognostic Biomarkers in Patients with Localized Ewing Sarcoma: A Report from the Children’s Oncology Group

BACKGROUND: A growing collection of retrospective studies have suggested that TP53 mutations and/or CDKN2A deletions have prognostic significance in Ewing sarcoma. We sought to evaluate these variables in patients with localized disease treated prospectively on a single Children’s Oncology Group pro...

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Publicado en:Pediatr Blood Cancer
Autores principales: Lerman, Daniel M., Monument, Michael J., McIlvaine, Elizabeth, Liu, Xiao-qiong, Huang, Dali, Monovich, Laura, Beeler, Natalie, Gorlick, Richard G., Marina, Neyssa M., Womer, Richard B., Bridge, Julia A., Krailo, Mark D., Randall, R. Lor, Lessnick, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376595/
https://ncbi.nlm.nih.gov/pubmed/25464386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25340
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