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p53 Loss Increases the Osteogenic Differentiation of BMSCs

The tumor suppressor, p53, plays a critical role in suppressing osteosarcoma. Bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) have been suggested to give rise to osteosarcomas. However, the role of p53 in BMSCs has not been extensively explored. Here, we r...

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Vydáno v:Stem Cells
Hlavní autoři: He, Yunlong, de Castro, Luis F, Shin, Min Hwa, Dubois, Wendy, Yang, Howard H., Jiang, Shunlin, Mishra, Pravin J., Ren, Ling, Gou, Hongfeng, Lal, Ashish, Khanna, Chand, Merlino, Glenn, Lee, Maxwell, Robey, Pamela G., Huang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376591/
https://ncbi.nlm.nih.gov/pubmed/25524638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1925
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