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3-iodothyroacetic acid, a metabolite of thyroid hormone, induces itch and reduces threshold to noxious and to painful heat stimuli in mice
BACKGROUND AND PURPOSE: Itch is associated with increased sensitization to nociceptive stimuli. We investigated whether 3-iodothyroacetic acid (TA1), by releasing histamine, induces itch and increases sensitization to noxious and painful heat stimuli. EXPERIMENTAL APPROACH: Itch was evaluated after...
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Publicado en: | Br J Pharmacol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
BlackWell Publishing Ltd
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376462/ https://ncbi.nlm.nih.gov/pubmed/25439265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13032 |
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