3-iodothyroacetic acid, a metabolite of thyroid hormone, induces itch and reduces threshold to noxious and to painful heat stimuli in mice

BACKGROUND AND PURPOSE: Itch is associated with increased sensitization to nociceptive stimuli. We investigated whether 3-iodothyroacetic acid (TA1), by releasing histamine, induces itch and increases sensitization to noxious and painful heat stimuli. EXPERIMENTAL APPROACH: Itch was evaluated after...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Laurino, Annunziatina, De Siena, Gaetano, Resta, Francesco, Masi, Alessio, Musilli, Claudia, Zucchi, Riccardo, Raimondi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376462/
https://ncbi.nlm.nih.gov/pubmed/25439265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13032
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