TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus

BACKGROUND AND PURPOSE: Transient receptor potential vanilloid type 4 (TRPV4) and calcium-activated potassium channels (K(Ca)) mediate osmosensing in many tissues. Both TRPV4 and K(Ca) channels are found in the paraventricular nucleus (PVN) of the hypothalamus, an area critical for sympathetic contr...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Autores principales: Feetham, C H, Nunn, N, Lewis, R, Dart, C, Barrett-Jolley, R
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376454/
https://ncbi.nlm.nih.gov/pubmed/25421636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13023
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