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Differential sensitivity of TREK–1, TREK–2 and TRAAK background potassium channels to the polycationic dye ruthenium red
BACKGROUND AND PURPOSE: Pharmacological separation of the background potassium currents of closely related K(2P) channels is a challenging problem. We previously demonstrated that ruthenium red (RR) inhibits TASK-3 (K(2)(P)9.1), but not TASK-1 (K(2)(P)3.1) channels. RR has been extensively used to d...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Br J Pharmacol |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BlackWell Publishing Ltd
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376452/ https://ncbi.nlm.nih.gov/pubmed/25409575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13019 |
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