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Synthesis and therapeutic effect of styrene–maleic acid copolymer-conjugated pirarubicin

Previously, we prepared a pirarubicin (THP)-encapsulated micellar drug using styrene–maleic acid copolymer (SMA) as the drug carrier, in which active THP was non-covalently encapsulated. We have now developed covalently conjugated SMA-THP (SMA-THP conjugate) for further investigation toward clinical...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Tsukigawa, Kenji, Liao, Long, Nakamura, Hideaki, Fang, Jun, Greish, Khaled, Otagiri, Masaki, Maeda, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376435/
https://ncbi.nlm.nih.gov/pubmed/25529761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12592
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