Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

Both BRCA1 and Beclin 1 (BECN1) are tumor suppressor genes, which are in close proximity on the human chromosome 17q21 breast cancer tumor susceptibility locus and are often concurrently deleted. However, their importance in sporadic human breast cancer is not known. To interrogate the effects of BE...

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Vydáno v:EBioMedicine
Hlavní autoři: Tang, Hao, Sebti, Salwa, Titone, Rossella, Zhou, Yunyun, Isidoro, Ciro, Ross, Theodora S., Hibshoosh, Hanina, Xiao, Guanghua, Packer, Milton, Xie, Yang, Levine, Beth
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376376/
https://ncbi.nlm.nih.gov/pubmed/25825707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.01.008
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