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IMPACT OF AZITHROMYCIN TREATMENT ON MACROPHAGE GENE EXPRESSION IN SUBJECTS WITH CYSTIC FIBROSIS

BACKGROUND: Azithromycin treatment improves clinical parameters in patients with CF, and alters macrophage activation from a pro-inflammatory (M1) phenotype to a pro-fibrotic, alternatively activated (M2) phenotype. The transcriptional profile of cells from patients receiving azithromycin is unknown...

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Detalhes bibliográficos
Publicado no:J Cyst Fibros
Main Authors: Cory, Theodore J., Birket, Susan E., Murphy, Brian S., Hayes, Don, Anstead, Michael I, Kanga, Jamshed F., Kuhn, Robert J., Bush, Heather M., Feola, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376357/
https://ncbi.nlm.nih.gov/pubmed/24018177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2013.08.007
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