FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration. Most cases of ALS are sporadic (SALS), but about 5-10% of ALS cases are familial (FALS). Recent studies have shown that mutations in FUS are causal in approximately 4-5% of FALS and some apparent SALS ca...

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Pubblicato in:Ann Neurol
Autori principali: Deng, Han-Xiang, Zhai, Hong, Bigio, Eileen H., Yan, Jianhua, Fecto, Faisal, Ajroud, Kaouther, Mishra, Manjari, Ajroud-Driss, Senda, Heller, Scott, Sufit, Robert, Siddique, Nailah, Mugnaini, Enrico, Siddique, Teepu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376270/
https://ncbi.nlm.nih.gov/pubmed/20517935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22051
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