OARSI–OMERACT initiative: defining thresholds for symptomatic severity and structural changes in disease modifying osteoarthritis drug (DMOAD) clinical trials

OBJECTIVE: Total joint replacement has been proposed as an endpoint in disease modifying osteoarthritis drug (DMOAD) randomized clinical trials (RCTs); however, disparities have generated concerns regarding this outcome. A combined Osteoarthritis Research Society International (OARSI)/Outcome Measur...

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Vydáno v:Osteoarthritis Cartilage
Hlavní autoři: Manno, R.L., Bingham, C.O., Paternotte, S., Gossec, L., Halhol, H., Giacovell, G., Rovati, L., Mazzuca, S.A., Clegg, D.O., Shi, H., Tajana Messi, E., Lanzarotti, A., Dougados, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375956/
https://ncbi.nlm.nih.gov/pubmed/22178465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2011.11.013
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