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Effects of bleomycin A5 on caspase-3, P53, bcl-2 expression and telomerase activity in vascular endothelial cells

OBJECTIVE: The aim of this study was to investigate the molecular mechanism of bleomycin A5 in inducing the apoptosis of human umbilical vein endothelial cells (ECV304). MATERIALS AND METHODS: ECV304 cells were cultured and passaged, and then were divided into control group and three treatment group...

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Detalhes bibliográficos
Publicado no:Indian J Pharmacol
Main Authors: Huang, Yi-Deng, Li, Ping, Tong, Xiao, He, Yue, Zhuo, Yang, Xia, Si-Wen, Luo, Xing-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375820/
https://ncbi.nlm.nih.gov/pubmed/25821312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.150337
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