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Effects of Orexin 2 Receptor Activation on Apnea in the C57BL/6J Mouse

BACKGROUND: The hypothesis was that an orexin 2 receptor (OX2R) agonist would prevent sleep-related disordered breathing. METHODS: In C57BL/6J (B6) mice, body plethysmography was performed with and without EEG monitoring of state (wakefulness, NREM and REM sleep). Outcome was apnea rate/hr during sl...

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Publicat a:Respir Physiol Neurobiol
Autors principals: Moore, Michael W., Akladious, Afaf, Hu, Yufen, Azzam, Sausan, Feng, Pingfu, Strohl, Kingman P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375729/
https://ncbi.nlm.nih.gov/pubmed/24929062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2014.03.014
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