Stochastic Model of Endothelial TRPV4 Calcium Sparklets: Effect of Bursting and Cooperativity on EDH

We examined the endothelial transient receptor vanilloid 4 (TRPV4) channel’s vasodilatory signaling using mathematical modeling. The model analyzes experimental data by Sonkusare and coworkers on TRPV4-induced endothelial Ca(2+) events (sparklets). A previously developed continuum model of an endoth...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Parikh, Jaimit, Kapela, Adam, Tsoukias, Nikolaos M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2015
Gaiak:
Systems Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375679/
https://ncbi.nlm.nih.gov/pubmed/25809269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.01.034
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