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Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: Evidence from two independent cohorts

Polygenic risk scores, based on risk variants identified in genome-wide-association-studies (GWAS), explain a considerable portion of the heritability for schizophrenia (SZ) and bipolar disorder (BD). However, little is known about the combined effects of these variants, although polygenic neuroimag...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Oertel-Knöchel, Viola, Lancaster, Thomas M., Knöchel, Christian, Stäblein, Michael, Storchak, Helena, Reinke, Britta, Jurcoane, Alina, Kniep, Jonathan, Prvulovic, David, Mantripragada, Kiran, Tansey, Katherine E., O’Donovan, Michael C., Owen, Michael J., Linden, David E.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375641/
https://ncbi.nlm.nih.gov/pubmed/25844328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2015.03.005
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