Tumor-secreted Hsp90 Subverts Polycomb Function to Drive Prostate Tumor Growth and Invasion

Prostate cancer remains the second highest contributor to male cancer-related lethality. The transition of a subset of tumors from indolent to invasive disease is associated with a poor clinical outcome. Activation of the epithelial to mesenchymal transition (EMT) genetic program is a major risk fac...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nolan, Krystal D., Franco, Omar E., Hance, Michael W., Hayward, Simon W., Isaacs, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375482/
https://ncbi.nlm.nih.gov/pubmed/25670862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.637496
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