Simvastatin for the Prevention of Exacerbations in Moderate-to-Severe COPD

BACKGROUND: Retrospective studies have shown that statins decrease the rate and severity of exacerbations, the rate of hospitalization, and mortality in chronic obstructive pulmonary disease (COPD). We prospectively studied the efficacy of simvastatin in preventing exacerbations in a large, multicen...

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Udgivet i:N Engl J Med
Main Authors: Criner, G.J., Connett, J.E., Aaron, S.D., Albert, R.K., Bailey, W.C., Casaburi, R., Cooper, J.A.D., Curtis, J.L., Dransfield, M.T., Han, M.K., Make, B., Marchetti, N., Martinez, F.J., Niewoehner, D.E., Scanlon, P.D., Sciurba, F.C., Scharf, S.M., Sin, D.D., Voelker, H., Washko, G.R., Woodruff, P.G., Lazarus, S.C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375247/
https://ncbi.nlm.nih.gov/pubmed/24836125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1403086
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