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Parkinsonism in Phenylketonuria: A Consequence of Dopamine Depletion?
Phenylketonuria (PKU) is caused by a deficiency or inactivity of the enzyme phenylalanine hydroxylase that converts phenylalanine (Phe) to tyrosine (Tyr). It has been proposed that a reduction of brain Tyr levels, as well as reduced activity of the key regulatory enzyme of dopamine (DA) synthesis ty...
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| Pubblicato in: | JIMD Rep |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375126/ https://ncbi.nlm.nih.gov/pubmed/25614310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2014_386 |
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