Stimulation of glucagon-like peptide-1 secretion downstream of the ligand-gated ion channel TRPA1

Stimulus-coupled incretin secretion from enteroendocrine cells plays a fundamental role in glucose homeostasis, and could be targeted for the treatment of type-2 diabetes. Here, we investigated the expression and function of transient receptor potential (TRP) ion channels in enteroendocrine L-cells...

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Vydáno v:Diabetes
Hlavní autoři: Emery, Edward C., Diakogiannaki, Eleftheria, Gentry, Clive, Psichas, Arianna, Habib, Abdella M., Bevan, Stuart, Fischer, Michael J. M., Reimann, Frank, Gribble, Fiona M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375100/
https://ncbi.nlm.nih.gov/pubmed/25325736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0737
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