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Quantitative high-throughput screening data analysis: challenges and recent advances
In vitro HTS holds much potential to advance drug discovery and provide cell-based alternatives for toxicity testing. In quantitative HTS, concentration–response data can be generated simultaneously for thousands of different compounds and mixtures. However, nonlinear modeling in these multiple-conc...
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| Udgivet i: | Drug Discov Today |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375054/ https://ncbi.nlm.nih.gov/pubmed/25449657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.10.005 |
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