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Quantitative high-throughput screening data analysis: challenges and recent advances

In vitro HTS holds much potential to advance drug discovery and provide cell-based alternatives for toxicity testing. In quantitative HTS, concentration–response data can be generated simultaneously for thousands of different compounds and mixtures. However, nonlinear modeling in these multiple-conc...

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Bibliografiske detaljer
Udgivet i:Drug Discov Today
Hovedforfatter: Shockley, Keith R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375054/
https://ncbi.nlm.nih.gov/pubmed/25449657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.10.005
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