Antithrombin III Deficiency in Indian Patients with Deep Vein Thrombosis: Identification of First India Based AT Variants Including a Novel Point Mutation (T280A) that Leads to Aggregation

Antithrombin III (AT) is the main inhibitor of blood coagulation proteases like thrombin and factor Xa. In this study we report the identification and characterization of several variants of AT for the first time in Indian population. We screened 1950 deep vein thrombosis (DVT) patients for AT activ...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bhakuni, Teena, Sharma, Amit, Rashid, Qudsia, Kapil, Charu, Saxena, Renu, Mahapatra, Manoranjan, Jairajpuri, Mohamad Aman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374914/
https://ncbi.nlm.nih.gov/pubmed/25811371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121889
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