Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial

IMPORTANCE: Severely injured patients experiencing hemorrhagic shock often require massive transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red blood cells), defined as damage control resuscitation, has been associated with improved outcomes; however, there h...

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Pubblicato in:JAMA
Autori principali: Holcomb, John B., Tilley, Barbara C., Baraniuk, Sarah, Fox, Erin E., Wade, Charles E., Podbielski, Jeanette M., del Junco, Deborah J., Brasel, Karen J., Bulger, Eileen M., Callcut, Rachael A., Cohen, Mitchell Jay, Cotton, Bryan A., Fabian, Timothy C., Inaba, Kenji, Kerby, Jeffrey D., Muskat, Peter, O’Keeffe, Terence, Rizoli, Sandro, Robinson, Bryce R. H., Scalea, Thomas M., Schreiber, Martin A., Stein, Deborah M., Weinberg, Jordan A., Callum, Jeannie L., Hess, John R., Matijevic, Nena, Miller, Christopher N., Pittet, Jean-Francois, Hoyt, David B., Pearson, Gail D., Leroux, Brian, van Belle, Gerald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374744/
https://ncbi.nlm.nih.gov/pubmed/25647203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2015.12
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